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Tiny Robots Crawl Through Mouse's Stomach To Release Antibiotics

Wed, 08/16/2017 - 20:02
Tiny robotic drug deliveries could soon be treating diseases inside your body. For the first time, micromotors -- autonomous vehicles the width of a human hair -- have cured bacterial infections in the stomachs of mice, using bubbles to power the transport of antibiotics. From a report: "The movement itself improves the retention of antibiotics on the stomach lining where the bacteria are concentrated," says Joseph Wang at the University of California San Diego, who led the research with Liangfang Zhang. In mice with bacterial stomach infections, the team used the micromotors to administer a dose of antibiotics daily for five days. At the end of the treatment, they found their approach was more effective than regular doses of medicine. The tiny vehicles consist of a spherical magnesium core coated with several different layers that offer protection, treatment, and the ability to stick to stomach walls. After they are swallowed, the magnesium cores react with gastric acid to produce a stream of hydrogen bubbles that propel the motors around. This process briefly reduces acidity in the stomach. The antibiotic layer of the micromotor is sensitive to the surrounding acidity, and when this is lowered, the antibiotics are released.

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Google Updates Docs, Sheets and Slides With New Collaboration Features

Wed, 08/16/2017 - 19:22
An anonymous reader writes: G Suite, Google's set of online productivity tools, is getting a major update today that adds a number of new features to Google Docs, Sheets and Slides. Most of these updates focus around collaboration, but the service is also getting support for Google Cloud Search and the company is adding new templates and add-ons from partners like LegalZoom, DocuSign, LucidChart and others. [...] Google Docs Sheets and Slides now lets you track changes by saving multiple versions of a document with different names. The new integration with Google Cloud Search in Docs and Slides means that G Suite Business and Enterprise users will now be able to quickly find the right information from their internal documents without having to leave the editor.

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Amazon Will Pay Developers With the Most Engaging Alexa Skills

Wed, 08/16/2017 - 18:41
Amazon today announced a new program to bring revenue to developers of Alexa skills based on how much engagement their voice app is able to generate among users of Alexa-enabled devices. From a report: Amazon appears to be the first of the major tech companies with AI assistants and third-party integrations -- like Google, Samsung, Apple, and Microsoft -- with a program to compensate developers based on engagement created by their voice app. Metrics used to measure engagement of an Alexa skill include minutes of usage, new customers, customer ratings, and return visitors, an Amazon spokesperson told VentureBeat. Developers of Alexa skills in the U.S., U.K., and Germany are eligible to join. Developers with a skill active in all three countries will receive separate payments based on engagement in each country.

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Higher Minimum Wages Bring Automation and Job Losses, Study Suggests

Wed, 08/16/2017 - 18:01
An anonymous reader shares a report via email: As of the start of the year, 19 U.S. states had raised minimum wages, dramatizing a long simmering debate: Do minimum wages kill jobs, and make the working class worse off in the end? Or do they simply make them a little richer, with little or no loss to overall employment? In a new paper, economists Grace Lordan of the London School of Economics and David Neumark of UC Irvine parse 35 years of census data and come down on the worse-off side: For lower-skill jobs like bookkeepers and assembly-line workers, they say, higher minimum wages encourage employers to automate -- according to their calculations, a $1 increase can cost tens of thousands of jobs nationally.

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New Work Suggests That P Is Not Equal To NP

Wed, 08/16/2017 - 17:20
New submitter cccc828 writes: In a new paper Norbert Blum tackles the P=NP question and finds them to be not equal. While this is exciting news (for theoretical computer scientists at least), remember that there is a long list of findings pointing either way.

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Ask Slashdot: Female Engineers, Could You Please Share Your Thoughts On the Google Memo

Wed, 08/16/2017 - 16:40
Reader joshtops writes: The widely circulated memo written by software engineer James Damore has become the talking point across companies in Silicon Valley, and elsewhere. In an interesting take, The Economist on Tuesday argued with the scientific or otherwise assumptions made by Damore. I was wondering what female engineers -- or females in other STEM beats -- think of the memo.

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Apple Is Bringing a Billion Dollar Checkbook To Hollywood and Wants To Buy 10 TV Shows

Wed, 08/16/2017 - 16:00
Apple is officially open for business in Hollywood. From a report: The company is telling content makers it wants to spend $1 billion on its own stuff over the next year. That's music to studios' ears, and a tune they have been expecting for some time -- especially after Apple hired two top Sony TV executives in June. We still don't know what Apple wants to do with that content: The Wall Street Journal says Apple wants to make up to 10 "Game of Thrones" -- or "House of Cards"-scale shows, but that's not enough to launch a full-scale subscription service.

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WordPress Bans Fascist Website Linked To Charlottesville Killer

Wed, 08/16/2017 - 15:00
tedlistens writes: WordPress has said that it does not censor websites like that of self-proclaimed fascist group Vanguard America. But last night, the group's site was taken offline for violating the company's terms of service. The about-face was likely prompted by Vanguard's participation in last weekend's Unite the Right rallies in Charlottesville, Virginia, during which James Alex Fields drove his car into a crowd, killing one person and injuring 19. Fields has claimed allegiance to Vanguard America; the group denies that Fields was a member. For WordPress to drop a site, even a fascist site, is a very big deal; the same is true of GoDaddy's and Google's decision to drop their registration of neo-Nazi site the Daily Stormer (another site that GoDaddy previously said would be permitted on free speech grounds). WordPress hasn't explained the shift in its approach to the website: the company's user agreement and terms of service have not changed since Charlottesville. That policy, like that of other tech platforms, has long stood by strict neutrality and freedom of expression. That may now be changing.

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WordPress Bans Fascist Website Linked To Charlottesville Killer

Wed, 08/16/2017 - 15:00
tedlistens writes: WordPress has said that it does not censor websites like that of self-proclaimed fascist group Vanguard America. But last night, the group's site was taken offline for violating the company's terms of service. The about-face was likely prompted by Vanguard's participation in last weekend's Unite the Right rallies in Charlottesville, Virginia, during which James Alex Fields drove his car into a crowd, killing one person and injuring 19. Fields has claimed allegiance to Vanguard America; the group denies that Fields was a member. For WordPress to drop a site, even a fascist site, is a very big deal; the same is true of GoDaddy's and Google's decision to drop their registration of neo-Nazi site the Daily Stormer (another site that GoDaddy previously said would be permitted on free speech grounds). WordPress hasn't explained the shift in its approach to the website: the company's user agreement and terms of service have not changed since Charlottesville. That policy, like that of other tech platforms, has long stood by strict neutrality and freedom of expression. That may now be changing.

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Energy Drinks May Trigger Future Substance Use, Says Study

Wed, 08/16/2017 - 12:00
New research suggests persistent consumption of energy drinks may predispose young adults to substance use. "Investigators, led by Amelia M. Arria, PhD, School of Public Health, University of Maryland, College Park, found that college students who regularly drink highly caffeinated energy drinks were at increased risk for later use of alcohol, cocaine, or prescription stimulants," reports Medscape. From the report: The research included students enrolled in an ongoing longitudinal study that began in 2004 at a large public university. The analysis included 1099 participants (54% women; 72% non-Hispanic white) who completed at least one annual assessment in which patterns of energy drink consumption were assessed. In interviews, participants were asked which energy drinks they had consumed, and how often, in the past year. They were categorized into three patterns of use: Frequent (52 or more days); Occasional (12 - 51 days); Infrequent (1 - 11 days). The investigators found that sensation seeking, conduct problems, and behavioral dysregulation were all positively associated with a higher probability of energy drink consumption, with the nonuse group having the lowest and the persistent group the highest risk scores. The study was published in the journal Drug and Alcohol Dependence.

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Google Allo For Chrome Finally Arrives, But Only For Android Users

Wed, 08/16/2017 - 09:00
Google Allo, the chat app that arrived on the iPhone and Android devices last year, now has a web counterpart. Head of product for Allo and video chat app Duo, Amit Fulay, tweeted: "Allow for web is here! Try it on Chrome today. Get the latest Allo build on Android before giving it a spin." Engadget reports: To give it a go, you'll need to open the Allo app on your device and use that to scan a QR code you can generate at this link. Once you've scanned the code, Allo pulls up your chat history and mirrors all the conversations you have on your phone. Most of Allo's key features, including smart replies, emoji, stickers and most importantly the Google Assistant are all intact here. In fact, this is the first time you can really get the full Google Assistant experience through the web; it's been limited to phones and Google Home thus far.

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Scientists Finally Unlock the Recipe For Magic Mushrooms

Wed, 08/16/2017 - 05:30
An anonymous reader writes: Aside from being a schedule 1 drug, scientists haven't fully understood the chemistry behind how mushrooms produce the chemical psilocybin -- until now. A new study may finally lay the groundwork for a medical-grade psilocybin patients can take. Gizmodo reports: "Living things make molecules through a series of chemical reactions, similar to how car makers produce cars on assembly lines. Enzymes act as the workers/robots, speeding up the reactions by helping put the pieces together. Actually making psilocybin requires mapping the biological factory. A 1968 paper (obviously it was in 1968) offered a proposed order of events leading to a finished psilocybin molecule, by adding radioactive elements and watching what happened to them on the assembly line. The researchers thought that maybe tryptophan, the amino acid everyone wrongly says makes you sleepy, was the first piece, which then went through four successive steps to become the finished product. The new study shows that the 1968 paper got the order wrong, and introduces the responsible genes and enzymes, the workers that do the specific task to get the final product. This time around, mapping the factory required sequencing the genomes of two magic mushroom species, Psilocybe cubensis and Psilocybe cyanescens. Then, the researchers found exactly which genes produce the required enzymes and spliced them into E. coli bacteria. Using those enzymes, they were able to rebuild the factory and create their own psilocybin." The study has been published in the German journal Angewandte Chemie.

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Intel Officially Reveals Post-8th Generation Core Architecture Code Name: Ice Lake, Built On 10nm+

Wed, 08/16/2017 - 04:05
Intel has confirmed the existence of a new processor family called Ice Lake that will be made on Intel's 10nm+ process. The company published basic information on the Ice Lake architecture on their codename decoder. AnandTech reports: This is an unexpected development as the company has yet to formally detail (let alone launch) the first 10nm Core architecture -- Cannon Lake -- and it's rare these days for Intel to talk more than a generation ahead in CPU architectures. Equally as interesting is the fact that Intel is calling Ice Lake the successor to their upcoming 8th generation Coffee Lake processors, which codename bingo aside, throws some confusion on where the 14nm Coffee Lake and 10nm Cannon Lake will eventually stand. As a refresher, the last few generations of Core have been Sandy Bridge, Ivy Bridge, Broadwell, Haswell, Skylake, with Kaby Lake being the latest and was recently released at the top of the year. Kaby Lake is Intel's third Core product produced using a 14nm lithography process, specifically the second-generation '14 PLUS' (or 14+) version of Intel's 14nm process. Working purely on lithographic nomenclature, Intel has three processes on 14nm: 14, 14+, and 14++. As shown to everyone at Intel's Technology Manufacturing Day a couple of months ago, these will be followed by a trio of 10nm processes: 10nm, 10nm+ (10+), and 10++. On the desktop, Core processors will go from 14 to 14+ to 14++, such that we move from Skylake to Kaby Lake to Coffee Lake. On the Laptop side, this goes from 14 to 14+ to 14++/10, such that we move from Skylake to Kaby Lake to Coffee Lake like the desktops, but also that at some time during the Coffee Lake generation, Cannon Lake will also be launched for laptops. The next node for both after this is 10+, which will be helmed by the Ice Lake architecture.

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Toyota Patents Cloaking Device To Make Car Pillars Appear Transparent

Wed, 08/16/2017 - 03:25
Toyota has patented a cloaking device that aims to make big, chunky car pillars transparent. The "apparatuses and methods for making an object appear transparent" which Toyota just patented uses cleverly placed mirrors to bend light around an object making it visible from the other side. The Drive reports: So you're not really seeing through the pillars, you're seeing around them. This is a much cheaper option than adding more cameras and screens all over the place and much more realistic than Harry Potter's invisibility cloak. The patent was filed with the U.S. patent office by Toyota North America, so if Toyota does go forward with this technology, we can probably expect to see it in cars in the U.S.

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Amazon Adds 'Instant Pickup Points' In US Brick-And-Mortar Push

Wed, 08/16/2017 - 02:45
An anonymous reader quotes a report from Reuters: Amazon is rolling out U.S. pickup points where shoppers can retrieve items immediately after ordering them, shortening delivery times from hours to minutes in its latest move into brick-and-mortar retail. The world's largest online retailer has launched 'Instant Pickup' points around five college campuses, such as the University of California at Berkeley, it said on Tuesday. Amazon has plans to add the program to more sites by the end of the year. Shoppers on Amazon's mobile app can select from several hundred fast-selling items at each location, from snacks and drinks to phone chargers. Amazon employees in a back room then load orders into lockers within two minutes, and customers receive bar codes to access them.

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App Developers Should Charge More If They Want People To Buy Subscriptions, Suggests Report

Wed, 08/16/2017 - 02:05
A new report from Liftoff, a Silicon Valley-based mobile app marketing and retargeting firm, says that subscription-based apps may do better if developers charge a higher price for services, rather than setting prices too low to lure users in initially. The Verge reports: The Liftoff report, which analyzed data gathered between June 2016 and June 2017, categorized app subscriptions into low-cost monthly subs ($0.99 to $7), medium ($7 to $20), and high-cost subs ($20 to $50), while also factoring the cost of acquisition per customer. The company found that apps in the medium price range had the highest conversion rate -- 7.16 percent -- and the lowest cost to acquire a subscriber, at just over $106 dollars. This was five times higher than the rate of people who subscribed to apps when the apps were in the low-cost category. This may partly be because streaming media apps, like Netflix and Spotify, have already conditioned people to pay around $10 a month for services. But it also might be attributable to the sunk cost fallacy, Liftoff says: the "cognitive bias people have that makes them stay the course because they have already spent time or resources on it." The report also examines apps that fulfill "need states," like dating apps or cloud services. These have the potential to offer services that customers are willing to pay for, again and again. But, according to Liftoff, utility apps have a much higher install-to-subscriber rate compared to dating apps. Blame those who eventually find love?

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Neo-Nazi Site The Daily Stormer Moves To Dark Web After Shutdown

Wed, 08/16/2017 - 01:20
After being shutdown by Google and GoDaddy, prominent neo-Nazi website The Daily Stormer has moved their site to the dark web. "The new site is now only available through the Tor network, which allows users to set up their own domains," reports VICE News. "The original site, Dailystormer.com, is now fully offline." From the report: The homepage, as of Tuesday morning, contained articles that make light of the car ramming attack that claimed the life of 32-year-old Heather Heyer; admonish the "Jew media;" liberally employ various racial epithets; and, in a less offensive post, provided an update on which characters are available on Pokemon Go. In a statement, the site's founder promised to bring his site back online. "The Daily Stormer will be live in internet prison with drug dealers, terrorists and perverts, which is where we've been exiled to, for all time," Andrew Anglin said in a statement sent to VICE News. "We should have a real domain online within 24 hours. If it gets shut down again, people will know we are on the black web."

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Plants 'Hijacked' To Make Polio Vaccine

Wed, 08/16/2017 - 00:40
Plants have been "hijacked" to make polio vaccine in a breakthrough with the potential to transform vaccine manufacture, say scientists. From a report: The team at the John Innes Centre, in Norfolk, says the process is cheap, easy and quick. As well as helping eliminate polio, the scientists believe their approach could help the world react to unexpected threats such as Zika virus or Ebola. Experts said the achievement was both impressive and important. The vaccine is an "authentic mimic" of poliovirus called a virus-like particle. Outwardly it looks almost identical to poliovirus but -- like the difference between a mannequin and person -- it is empty on the inside. It has all the features needed to train the immune system, but none of the weapons to cause an infection.

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Guam Radio Stations Accidentally Conduct Emergency Alert Amid North Korea Threat

Wed, 08/16/2017 - 00:00
the_webmaestro writes: A couple of radio stations in Guam conducted an unscheduled test of the Emergency Alert Broadcast System, sending some residents -- already on edge due to the back and forth between the North Korean regime and the tweets made by the President of the United States -- into a panic. From the Guam Homeland Security/Office of Civil Defense Facebook page: "The Offices of Guam Homeland Security and Civil Defense (GHS/OCD), in conjunction with the Mariana Regional Fusion Center (MRFC), our federal and military partners, continue to monitor the recent events surrounding North Korea and their threatening actions. Residents and visitors may have noticed at 12:25 a.m., an unscheduled test of the Emergency Alert Broadcast System (EAS) was triggered from KTWG/KSTO AM. The message read: 'A BROADCAST STATION OR CABLE SYSTEM HAS ISSUED A CIVIL DANGER WARNING FOR THE FOLLOWING COUNTIES/AREAS: Guam, Guam; AT 12:25 AM ON AUG 15, 2017 EFFECTIVE UNTIL 12:40 AM. MESSAGE FROM KTWGKSTO.' The unauthorized test was NOT connected to any emergency, threat or warning. GHS/OCD has worked with KSTO to ensure the human error will not occur again. There is no scheduled test of the EAS or All Hazards Alert Warning System sirens today." In addition, the Guam Power Authority (GPA) reported there were two scheduled outages, for emergency interruption of power, at 2:30 p.m. and 7 p.m., August 14: "Unrelated to the EAS unauthorized test, the Guam Power Authority (GPA) reported there were two scheduled outages, for emergency interruption of power, at 2:30 p.m. and 7 p.m., August 14 for customers located in Talofofo located along along Rte.17, Chalan J. Kindo, Vicente Borja Dr., Felix Dydasco St., Henry Simpson area to bus shelter by Bishop Street and other customers in these locations."

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Amazon Is Seeking $16 Billion Bond Sale For Whole Foods

Tue, 08/15/2017 - 23:20
An anonymous reader quotes a report from Bloomberg: Amazon is turning to the debt markets to fund the $13.7 billion acquisition of Whole Foods and power Jeff Bezos's planned conquest of the supermarket business. The world's largest online retailer is selling $16 billion of unsecured bonds in as many as seven parts, according to a person with knowledge of the matter. In a sign of market interest, the longest portion of the offering, a 40-year security may yield 1.45 percentage points above Treasuries, down from initial talk of 1.6 percentage points to 1.65 percentage points, said the person, who asked not to be identified as the deal is private. The sale marks the first bond-market foray since 2014 for Amazon and will support the purchase of the organic-food chain, according to a company statement. The partnership, which rattled the grocery world when announced in June, is expected to reduce prices at Whole Foods, an iconic yet struggling high-end grocery trying to lure more low- and middle-income shoppers. The deal could intensify a price war in an industry beset by razor-thin margins and persistent deflation.

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